Sternberg ED, Cook JA, Alou LPA, Assi SB, … Thomas MB
The Lancet202156 citationsOpen accessDOI 10.1016/s0140-6736(21)00250-6
Community trials
Proof at village scale
Cluster-randomised community trials (Phase III)
Evaluating the efficacy of malaria control interventions under real-world conditions, through entomological, epidemiological and sociological follow-up.
1 Entomological component
What we measure
- Density, diversity and composition of vector populations
- Infection rate and entomological inoculation rate
- Insecticide resistance and associated mechanisms
Methods
- Entomological collections and trapping
- Morphological and molecular identification of vectors
- Susceptibility tests, genetic and molecular analyses
2 Epidemiological and parasitological component
What we measure
- Malaria incidence and prevalence
- Parasite prevalence and density
- Circulating Plasmodium species
Methods
- Cross-sectional surveys and cohort follow-up
- Rapid diagnostic tests and microscopy
- Molecular identification of Plasmodium species
3 Sociological component
What we measure
- Acceptability and use of interventions
- Community knowledge, perceptions and practices
- Sociocultural factors influencing uptake
Methods
- Household surveys
- Individual interviews and focus group discussions
- Observation and qualitative analysis
WHO guidelines and testing standards
- Implementation guidance, Long-term community studies for ITNs (new tab)
Durability and efficacy of nets over three years of routine use
2026Current
- WHO guidelines for malaria (new tab)
WHO recommendations on malaria interventions
2026Current
Published studies
Sih C, Protopopoff N, KOFFI AA, Alou LPA, … Cook JA
Trials202411 citationsOpen accessDOI 10.1186/s13063-024-07969-2
N’Guessan R, Assi SB, KOFFI AA, Alou PLA, … Farenhorst M
Trials20233 citationsOpen accessDOI 10.1186/s13063-023-07639-9